HOW THE BRAIN WORKS

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

A Thousand Brains, A New Theory of Intelligence

By: Jeff Hawkins

                                   Narrated by : Jamie Renell, Richard Dawkins

Jeffrey Hawkins (Author, electrical engineer, neuro-science researcher, business person.)

Jeff Hawkins presents an enlightening and, to some, frightening view of humanity’s current condition and future existence. 

Enlightenment is in the explanation of how the brain works.  Fear is in Hawkins explanation of how human beings make their own choices, with inference that humans have free will.

Jeff Hawkins explains a brain has two fundamental parts.  One is a brain stem that extends from the limbic center of the brain. The new part is the neocortex.

The brain stem is the “old brain”, the seat of control for body function, with connection to the limbic mid-brain which contains emotion.  The “new brain” is an evolutionary consequence of “old brain” origin. The neocortex surrounds and sits on top of the brain stem and constitutes approximately 70% of the human brain.  The neocortex is Jeff Hawkins characterization as a “new brain”. 

The remarkable insight of the author is that these two brains are interconnected by cortical columns that give humans superior intelligence.  That insight opens the door to consciousness and the possibility of creating a dynamic relationship between man and machine.

Richard Dawkins, a British evolutionary biologist, writes a laudatory forward to “A Thousand Brains”.

Richard Dawkins comments give listeners clues to the momentous potential of Jeffrey Hawkins experimentally reproducible theory of how the brain works.  Richard Dawkins ground-breaking explanation of “The Selfish Gene” explains why Jeff Hawkins theory of “A Thousand Brains” has two fundamental parts, an “old brain” and a “new brain”.  Both brains are made up with cells with genes that have a singular purpose. Genes purpose is to genetically replicate themselves. Jeffrey Dawkins implies genes in the cells of the “old brain” came first and the “new brain” came later through natural selection.

Genes are deeply imbedded in cells, the basic building blocks of life.

Jeff Dawkins argues an old brain is the seat of life sustaining action with direct connection to the mid-brain below the neocortex. To Jeff Dawkins, a new brain is an evolutionary change for humans to reach beyond emotions and action for gene survival. The purpose of survival evolves with interaction between old and new brains to accommodate social change. The new brain recognizes gene survival requires more than a “kill or be killed” mentality inherent in “old brain” evolution.

Jeff Dawkins experimentally proves there are synaptic connections between new and old brains within cortical columns that offer choices for change to ensure gene survival.  That synaptic connection allows humans to draw on thousands of recorded memories from a person’s life.  These memories are hundreds of thousands of models of everything a human brain experiences.  As models they are only representations of reality, but humans make decisions based on those remembrances.

The flaw is that human decisions are made based on representations of reality, not necessarily true reality.  Experience models in human’ memory can be completely wrong. 

The implication of Jeff Hawkins’ research is two edged.  One edge leads to fictional characters like Dr. Moreau and Dr. Strangelove.  (Moreau is a mad scientist who creates “humanimals” and Strangelove is a fictional Nazi American advisor who wants to drop a nuclear bomb on the Soviet Union during the cold war.) The other edge may lead to a possible eternal future for humankind with travel to other worlds should this one become uninhabitable.

The first edge implies an “old brain” mad science geneticist who creates a software program for cortical columns to rule the world with an “old brain” use of force. 

The second edge is a software program for cortical columns that provides rational control of the “old brain” by the “new brain”. Both are intended to make decisions based on perceived circumstances for survival.  However, the “old brain” uses force, while the “new brain” uses memory of past experience and reasoned accommodation to circumstance. In either case, humans take advantage of genes survival imperative.  That imperative reinforces Richard Dawkins’ theory of the immortal gene that will do whatever it takes to survive.

Though the Dr. Moreau and Strangelove future is obviously negative, there is a flaw in Hawkins second edge.  It is the unreliability of human memory. Hawkins answer to this flaw is that a meld between human and machine mind can improve the accuracy of memory.  If memories are quickly and accurately recalled, machine/human choice is more likely to preserve life, at least a form of human life.

Still, one wonders who wins when there is conflict between human and machine memory.  Does the “old brain” overtake “new brain” cortical column software and respond with emotion and violence?

Jeff Hawkins endorses Richard Hawkins explanation of “The Selfish Gene”.  Evolution is simply a reflection of a gene’s desire to survive.  Jeff Hawkins infers a “new brain” uses a genetic survival meme that controls “old brain” inclinations. The question is—will the selfish gene of an “old brain” recognize this change as consistent with gene’s evolutionary imperative.

Jeff Hawkins believes A.I. research fails to follow the path of the “I” (intelligence) in A.I.  Jeff Hawkins has significantly contributed to human understanding of how the brain works.  His remarkable engineering perspective posits immense potential for artificial intelligence. However, if machines can truly be made to think and adapt, will they be allies or adversaries as their thinking evolves?  Hawkins, to avoid that possibility, suggests human brains and machines might be integrated to avoid extinction. With Richard Hawkins’ theory of gene survival instinct, a meld between human and machine assures, if not guarantees, human survival.   

With true A.I, constructive work can be done in inhospitable human environments like Mars.  However, to unleash machine intelligence requires a leap of faith.  Can humans trust machines without melding minds with machine technology?

Dawkins notes it is impossible for A.I., as it is presently being developed, to be capable of terra-forming another planet for human survival. Machines have to be able to think like humans in order to deal with the unknown difficulties of terra-forming another planet. Using cortical column programing to create thinking machines might offer the human race many worlds but nature has always gotten in the way of species immortality.

This is an easily understood book for non-scientists to appreciate where genetic science may lead humans. To some, it offers hope. To others, it denies existence of species demise (nature’s cycle of life and death), pre-destination, and belief in God.

LUMINARIES

It is clear in this biography that Einstein’s contribution to science is as immeasurable as aforementioned luminaries of politics, arts, and science. Einstein, and Newton stand as the elite of the elite in science. One hopes there are others in this century.

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Albert Einstein, Creator and Rebel

By Banesh Hoffmann, Helen Dukas

Narrated by : Wanda McCaddon

CO-AUTHORS OF “ALBERT EINSTEIN, CREATOR AND REBEL”

The impact of extraordinary human beings is partly the result of chosen facts–there repetition, and future generations’ revisions of history.  The best known are men, undoubtedly due to misogyny that reaches back to the earliest writings of history.  Whether because of misogyny or other reason, mostly men have had the greatest influence on the course of politics, arts, and science. None more than Aristotle, Jesus Christ, Leonardo da Vinci, Isaac Newton and Albert Einstein.

Banesh Hoffman and Helen Dukas reveal why Einstein is among a select group of extraordinary human beings.  Presumably, Hoffman (because he is a physicist) offers explanation of Einstein’s contribution to the world of science.  However, in an equally revealing light (because Dukas is secretary to Einstein), one presumes she offers understanding of Einstein’s personal correspondence and innate humanity.  To we who are not scientists, Dukas is the star of the book.  Whether searching for understanding of E=mc2 or Einstein’s humanity, this book is worth reading and re-reading.

Newton versus quantum mechanics.

Einstein did not overturn the physics of Isaac Newton, just as he did not deny the validity of quantum mechanics. 

Einstein added to Newton’s understanding of physics by confirming belief in quantum mechanics with the caveat that quantum mechanics does not reveal everything about physics of the universe.  Einstein argues to his last days–their remains an unrevealed fundamental truth about physics. He believes physics will explain why things exist and why manifestation of things is predictable.  Like the inviolate speed of light, Einstein insists there is a physics law that gives predictability rather than probabilistic answers for ways of the world.

Baruch Spinoza (1632-1677, Dutch philosopher of the Enlightenment, biblical critic.)

Einstein believes in God but it is the God of Spinoza. Einstein believes God is not a corporeal being but a principle.

To Spinoza, God is everything in nature.  Religions look at Einstein and Spinoza as heretics, and as some argue, atheists.  However, Einstein suggests “God does not play with dice”. He is saying there is a fundamental cause for everything in the world.  That fundamental cause is God. However, that God is nature which, like energy and mass, has equivalence. Einstein believes there is an unknown fundamental law that explains life’s predictable existence which will prove God is real because, in his view, nature is real and predictable.

Einstein clearly identifies himself as a Jew but in the sense of ethnic association, not religion.  Part of Einstein’s self-identity comes from his disgust with Germany and its systemic murder of Jews in the holocaust. 

Dukas reveals Einstein’s sponsorship of Jews who wish to escape Nazi Germany.  She notes that Israel asks Einstein to serve as President of Israel.  He is deeply honored but chooses not to accept because his life experience is as a scientist, not a politician.

Dukas explains Einstein has an implacable belief in scientific predictability and an unstoppable drive for proof.  Both authors make it clear that Einstein’s greatest discoveries come in his early twenties. He doggedly pursues intuitive truth, even when faced with experiments that fail to support his beliefs.  Einstein does not become discouraged. He casts failed experiment and mathematical calculation aside and re-doubles his effort to confirm his intuitive beliefs.

Einstein did not initially realize the potential of E=mc2 as a weapon because he thought too much energy would be required to create nuclear fission that would change mass into energy. 

With the discovery of neutrons by Otto Hahn and Fritz Strassmann in 1938, Einstein realizes there is destructive potential in his discovery of mass and energy equivalence.  Neutrons used to bombard particular fundamental atoms demonstrate transmutation of mass into energy.   That transmutation unleashes a cataclysmic force.

Einstein is shown to be an avid pacifist, but atrocities perpetrated by Germany in WWII leads him to recommend early efforts of America to create a nuclear bomb.  However, he is appalled by the bombs use in Japan.

The thought among Allied forces is that Germany would develop a nuclear bomb before Allied forces could end the war.  There is the suggestion by some that Germany’s last-ditch effort at the Battle of the Bulge was a desperate attempt to delay defeat to have time to develop a nuclear bomb.

It is clear in this biography that Einstein’s contribution to science is as immeasurable as aforementioned luminaries of politics, arts, and science.  Einstein, and Newton stand as the elite of the elite in science.  One hopes there are others in this century.

E=mc2

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Black Holes: Going to Extremes

Articles Published in Scientific American

Narrated by Alex Boyles

“Black Holes” is a brief compilation of 21st century “Scientific American” articles narrated in Audiobooks by Alex Boyles.  At the least, these articles stimulate interest in finding out more about the history of black holes. 

When were they discovered?  Why is their discovery important?  Why do they seem to contradict the experimentally proven theory of Quantum Mechanics?  Why should we care?

Karl Schwarzschild (1873-1916, German physicist, astronomer, and mathematician.)

The idea of black holes dates to research done by scientists in the early 20th century.  The first black hole is discovered by Karl Schwarzschild.  Schwarzschild was the director of the Astrophysical Observatory in Potsdam, Germany. 

In correspondence, Schwarzschild confirms Einstein’s mathematical theory of gravity as a form of matter that reinforces the famous equation E=mc2. 

John Wheeler (1911-2008, American theoretical physicist.)

Much later in the century, fellow physicist John Wheeler explains “Space-time tells matter how to move; matter tells space-time how to curve”.

The elemental particles of gravity are not clearly understood because they are too small for current scientific observation.  Black holes are evidence of gravity, but the evidence seems to conflict with experimentally proven theories of quantum mechanics.

The discovery of black holes is important because it may hold the secrets of gravity.  Gravity makes planets and objects within and on planets attract and repel.  Einstein explains how gravity distorts the fabric of the universe.

Einstein’s equation indicates that energy and mass are equivalent and therefor never lost.

Black holes absorb all things that fall within their gravitational field at their “event horizon”.

However, astronomical observation shows that black holes seem to disappear without any information, residual mass. or energy remaining. This defies the current theory of quantum mechanics and seemingly Einstein’s belief that mass and energy are equivalent and never lost.

Why should we care?  Quantum mechanics is a theory that defies certainty.  However, Einstein believed God did not play with dice.  He believed a future discovery will give humankind an all-encompassing understanding of nature, just as Einstein’s “energy and mass equivalence” offers a limited theory of nature.  Black hole existence and disappearance may hold the answer to an all-encompassing fundamental law of nature that explains everything about everything.

Maybe Einstein’s E=mc2 is confirmed (not denied) by the existence of black holes.  Maybe, black holes do not violate the equivalence of energy and mass even though information appears to be lost when a black hole disappears. 

Could all black holes in a universe act as though they are connected at a distance?  Maybe energy and mass equivalence is not lost but spookily transmitted to other black holes.  Einstein may yet be confirmed. Maybe there is a missed fundamental law of physics that offers a Newtonian order to the universe.

QUANTUM REALITY

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Cosmological Koans

A Journey to the Heart of Physical Reality

By Anthony Aguirre

Narrated by Jonathan Todd Ross

Anthony Aguirre (Author, theoretical cosmologist, Presidential Chair for the Physics of Infomration at U of C. in Santa Cruz)

Anthony Aquirre offers a modicum of insight (enlightenment) to the concept of quantum reality.  The use of the word modicum is not to suggest Aquirre’a effort is insignificant but understanding quantum reality remains fragmentary and obscure.

The title of the book is a clue to Aquirre’s fragmentary insight.  To begin with, one must know the definition of koan.  A koan is “a paradoxical anecdote or riddle, used in Zen Buddhism to demonstrate the inadequacy of logical reasoning with the intent of provoking enlightenment”. 

Aquirre tells a story of a wanderer whose peregrination leads to a meeting with a Jinn who explains life is pre-ordained and cannot be changed because of the laws of quantum reality. 

The Jinn tells the wanderer he can see the wanderer’s future because fundamental quantum particles of his being are known to the Jinn.  The Jinn can see how each particle interacts with the wanderer’s thoughts and action to determine what will happen in the wanderer’s future.  Though there are billions of interactions the Jinn can calculate probabilities of every action the wanderer will take in the future.

Quantum physics is a science of probability that examines the fabric of space-time.  Experiment confirms that infinitesimal quantum particles can be in two places at the same time. 

However, the particles cannot be both measured and located without effecting their path.  If the particles cannot be both measured and located, how can a future be precisely predicted?  Putting aside complexity and the problem of measurement and location to predict the future, Aquirre argues quantum physics has opened a new door to the nature of reality. 

Schrodinger’s cat in the box is either dead or alive but you cannot know without opening the box. 

Aquirre notes humans may see the world as fictive because reality is trapped in one’s mind which cannot see the fundamental particles of nature. 

The example would be “green” as a figment of an interaction of one’s mind with what the eye sees; not the essence of what is identified as color because there is no fundamental particle that is the color “green”.

Aquirre explains the arrow of time can only move forward.  Time travel to the past is science fiction.  Traveling to the past cannot happen based on quantum theory because the past is fixed. 

Aquirre is a cosmologist.  He discusses the ideas of a created and expanding universe.  He refers to the science of Gallio, Newton, Schrodinger, and Einstein.  There is a past and a present, but the past can never be relived, and the present is past as soon as it becomes present. 

There is only a present with a probabilistic future. The future can theoretically be predicted based on fundamental particles of a quantum universe, but it requires the capacity of a mythical Jinn who can compute an infinite number of variables.

Aquirre leaves listeners in Plato’s cave that shows only shadows of reality.

One comes away from “Cosmological Koans” with the belief that reality remains unknown.  Complete understanding of life’s truth (if there is one) rests in the future of science and mathematics, a supercomputer like a Jinn, or God.

WORLDS OF IMAGINATION

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Dawn of the New Everything (A Memoir)

By: Jaron Lanier  

Narrated by: Oliver Wyman

American computer philosopher, computer scientist, visual artist, and musician.

Both Da Vinci (as characterized by Walter Isaacson) and Jaron Lanier are self-effacing geniuses without formal education. Both manage to create worlds of imagination.

Lanier’s memoir illustrates how refinement of virtual reality is as groundbreaking as Da Vinci’s understanding of light.  History will not likely view Lanier as the Da Vinci of our era but there are interesting similarities. 

Not to carry the comparison too far, Lanier magnifies the value of imagination without limiting its potential for both human good and evil. 

Da Vinci designs weapons of war that purposely fed the ambitions of his era’s tyrants.

Lanier is one of the pioneers of facial recognition.  Facial recognition is a tool that can be used by humanities’ tyrants as well as benefactors.  In conjunction with digitizing the lives of everyone, facial recognition implies a “Brave New World” as eminently realizable. 

A visit to China reinforces potential loss of privacy and human volition with the advance of a digitized and monitored population.

One comes away from Lanier’s memoir with an appreciation for his candor about life and his unshaken belief in the value of technology.  He recognizes his personal imperfection while maintaining an optimistic view for the world’s rescue by AI as a tool rather than controller of human life.  There is some comfort in his opinion, but a listener reserves judgement based on the life Lanier has led.  He is undoubtedly a polymath but his memoir focuses more on pleasures than the reality of most people’s lives.

The principle of virtual reality lends itself to Lanier’s obsession with music and entertainment. 

Lanier is a musician, among many other talents.  He spends some of his time collecting and mastering abstruse musical instruments. 

One comes away from “Dawn of the New Everything” with the feeling that VR has greater potential for distraction than humanity’s betterment. There is respite from this perception with Lanier’s explanation of how VR is used for education and training. It is a virtual tool for medical and science education. 

On the other hand, VR is a tool for remote murder by a person guiding a drone.

B.F. Skinner, American psychologist, behaviorist, author, inventor, and social philosopher.

Lanier also notes that VR has the potential of making life conform to other’s interest.

The “Dawn of Everything” gives a clearer picture of what it was and is like to become a part of the Silicon Valley.  He candidly recounts his rise as a tech mogul, failure, and gadfly. 

Facebook and Twitter addiction are influencers with WMD potential.

Lanier’s memoir is at once enlightening and disheartening.  He offers a virtual picture of modern life that is influencing, but not yet controlling. Lanier is optimistic.  Many listeners will leave his memoir skeptical.

SMARTEST IN THE ROOM

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

How Not to Be Wrong

By: Jordan Ellenberg  

Narrated by Jordan Ellenberg

Jordan Ellenberg (Author, American mathematician, Professor of mathematics at University of Wisconsin-Madison).

Like listening to Brian Greene (a theoretical physicist), Jordan Ellenberg reminds one of what it must be like to be the smartest person in the room.  One feels better from the experience of listening to “How Not to Be Wrong”, but understanding will be a struggle for most non-mathematicians. A non-mathematician leaves Ellenberg’s book better informed, if not entirely enlightened.

A non-mathematician may be hesitant to take Ellenberg’s book in hand.  Ellenberg does not convince one that mathematics will always help one “…Not…Be Wrong”. However, Ellenberg convincingly argues mathematics will offer a better chance of being right.

Ellenberg is a professor of mathematics.  He capsulizes mathematics as the language of science.  He reveals how mathematics offers a qualified understanding of reality. 

It is impossible to deny the validity of Ellenberg’s claim that mathematics is the language of science.

It is difficult to conceive of truth without mathematics because it provides a basis for repeatable experimental results. However, we live in a world of probabilities according to quantum mechanics. That implies mathematics cannot be the sole determinate of truth.

Ellenberg shows how “right” is qualified by mathematical proof.  Like Brian Greene, Ellenberg shows how mathematics brings one closer to truth but only to the point of a “null hypothesis”.  A null hypothesis is a repeatable experiment where there is zero (null) difference in results.  Being right is dependent upon the same results from population samplings and relevant repeatable experiments.

What strikes at the heart of Ellenberg’s explanation of “How Not to Be Wrong” is human natures tendency to make events conform to plan.  Human beings can lie to themselves. 

Lying to oneself is the source of conspiracy theories based on the human strength and weakness of seeing patterns in nature.  Perceived patterns from observation may or may not meet the criteria of a “null hypothesis”.  Ellenberg suggests one should be skeptical of observed patterns that defy common sense.

What is disturbing about Ellenberg’s explanation of “How Not to Be Wrong” is that probability enters into the equation of truth. 

This is the same fundamental law noted by theoretical physicists like Brian Greene.  With the use of mathematics as the language of science, one can only expect a probability of truth: not certainty.

Ellenberg notes one must keep in mind–not being wrong is entirely different from being right.  Determination of whether one is right or wrong is two-edged where one edge offers a probability of being right while the other implies possibility of being wrong.  The uncertainty of probability is a lighted match that can burn down a forest of science.

That match is fanned into a flame by those who disparage all of science because of revised theories based on newly discovered facts. As an example–our recent experience with the former President of the United States who discredited the science of masking and distancing during the Covid 19 pandemic.

Ellenberg gives numerous examples of people who are misled by population sampling and the concept of correlation.  Human nature often misleads people to see patterns where cause is unrelated to effect.  Ellenberg argues that better understanding of mathematics can teach humans “How Not to Be Wrong”. 

Being right is always qualified by some level of probability.  Ellenberg explains repeatable experiment, with a level of consistency in mathematical proofs, is our way of not being wrong.  Good to know, but daunting to achieve when mathematics is the only avenue for understanding. 

Don’t we all want to know “How Not to Be Wrong”?  Is the language of mathematics the only avenue for understanding?  Therein lies the fear of realizing you are not the smartest person in the room.

LIVING LIFE

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Until the End of Time

By: Brian Greene  

Narrated by Brian Greene

Author, (American Theoretical Physicist)

There is a great deal to unpack in Brian Greene’s “Until the End of Time”.  As is true of many of Greene’s scientific observations, much of his self-effacing intelligence and science-based opinion is lost in the ignorance of his listeners, not to mention this listener.  However, where Greene’s beliefs intersect with one’s limited knowledge, his theory of the ending of time and life is immensely rewarding and enlightening.

Greene does not argue there is no God. However, he suggests modern science shows there is no reason for God to exist to create life. 

To Greene, there is more verifiable proof of life in science than verifiable proof of God in either science or religion.

In Greene’s thought, God and religion may have a great deal to do with sustaining human life, but in ways more sociological than religious.  Weather one is a believer, atheist, or agnostic makes no difference to Greene.  He carefully constructs an explanation of how science shows life may have come into existence, why stories of life may explain belief in God, and why humans are fundamentally different from other forms of life.  The fundamental point of “…the End of Time” has to do with human mortality.  Human mortality lies at the core of Greene’s view of time and life.

Greene suggests the laws of physics founded by luminaries like Newton, Einstein, Heisenberg, Bohr, and Erwin Schrodinger offer evidence for the basis for life on earth, with or without God.  Greene explains the principle of thermodynamics, the fundamental science of energy that creates and sustains life. 

Greene explains–the physics of energy (thermodynamics) ensures eventual death.  All life is pre-determined by the fundamental law of entropy.  The fate of time and life began with a bang.  This singular event disbursed tightly organized atomistic particles into a continually less organized space.

Greene notes that all forms of life are subject to entropy, a gradual decline from order to disorder.  Greene argues that entropy acts at an atomistic level to determine the fate of all living things. Greene suggest laws of quantum mechanics determine the course of life for all “living” things.

To Greene, humankind is free to make choices.  However, he argues humankind does not have free will.  The physics of science show that all living things cannot choose to live forever.  Humans can choose how to live, what to think, who to love, who to hate but they cannot choose one Nano second longer than what is dictated by the fundamental law of entropy.

Greene notes the science of Darwinian evolution and genetic inheritance is a relevant reinforcement of his argument for the inevitable extinction of life.  The entropy accompanying human habitation is evident in pollution of the air we breath and the water we drink.    (Though Greene does not address advances in genetic inheritance through gene manipulation, genetic manipulation does not negate Greene’s overriding concept of entropy.)

Just as earth’s environment slowly degrades, genetic inheritance as a process will eventually lead to extinction.  Humans, just as dinosaur’s, sabre tooth tigers, and Dodo birds will disappear. All life adapts to change until the speed of environmental change becomes greater than the speed of evolutionary adaptation.

Greene agues humankind’s recognition of mortality shapes lives as consequentially as evolution. The significance of Greene’s argument is that religion is founded on acknowledgement of eventual death.  Knowing that one cannot live forever, creates the desire for something beyond death.  Greene elaborates by arguing that human lack of control over natural events compels creation of stories about a Supreme Being. *

The big picture in “Until the End of Time” is that the world and life is heading for an end.   Based on the science of physics, there is an “…End of Time” for humankind, based on the immutable and experimentally proven laws of thermodynamics.  Entropy is evident in the science of quantum mechanics (the physical properties of nature at the scale of atoms and subatomic particles), and the science of a continually expanding universe.

What does this mean to us?  Humans still make their own choices on how to live, love, and hate in their lifetimes.  The singer, Bobby McFerrin, suggests “Don’t Worry Be Happy”.  Others suggest the meaning of life is to live in the moment.  Brian Greene suggests it is up to you.  Our lives and death may be pre-determined, but we have freedom to choose how we live, love, and work.

In re-thinking Greene’s belief in the physics of entropy, one wonders about the concept of energy never being destroyed. Einstein’s formula of E=MC2 implies our corporal bodies may die but atoms transmogrify. What does that suggest about the entropy of human life?

* Greene acknowledges the slim possibility of Devine existence but considers it much less probable based on the discipline of science and the existence of entropy.  Greene does not discount the comfort religion offers humankind, including the rituals that help one cope with life and the passing of loved ones.

EVOLVING PANDEMICS

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Mysteries of the Microscopic World

By: Bruce E. Fleury (Great Courses)

Lecturer-Professor Bruce E. Fleury

Bruce E. Fleury (Professor of Practice in the Dept. of Ecology and Evolutionary Biology at Tulane University)

“Mysteries of the Microscopic World” is a reflection on the “The Invisible Realm”, the world of bacteria, viruses, fungi, and protozoa. 

It is somewhat dated because of today’s history of Covid19.  However, Fleury offers a modern understanding of pandemics and the role germs play in human life.

Antonie van Leeuwenhoek (1632-1723)

Fleury explores a world unseen until the 17th century.  Antony van Leeuwenhoek is identified as the first to see the “…Microscopic World” in 1683. 

However, the microscopic world was not considered important until the 19th century when puerperal fever was found to be caused by germs.  A germ theory of disease originated with Ignaz Semmelweis, a Hungarian physician in the 1840s. Many babies were dying from puerperal fever because doctors were going straight from deceased patients’ autopsies to delivery operating rooms. 

An interesting side note by Fleury is Semmelweis’s germ theory required careful hand washing before delivering babies.  Washing hands is still not carefully followed, even by the medical profession.  Fleury suggests only 50% of doctors and nurses properly wash their hands.

In the late 1850s Louis Pasteur suggested the spread of microorganisms (germs) could explain infectious disease.  Pasteur, and later Robert Koch, began to isolate bacteria of diseases like anthrax, TB, and cholera.  The race for understanding the microscopic world’s relationship to disease is launched.

Fleury explains this microscopic world is not only a disease producer.  It also aids human existence by offering microorganisms that get rid of wastes and remove toxic chemicals from the body.  Fleury notes some humans die from microorganisms, but they cannot live without them.

Fleury explains how the microscopic world follows the same Darwinian evolutionary path as the macroscopic world.  The microscopic world, like the animal world, evolves with random adaptation that sustains all life.

The two edges of this microscopic world can cure or kill.  Fleury explains how this unseen world evolves in the same way the animal kingdom evolves.    Today’s Covid19 virus changes to preserve itself.  Covid19 evolves like any life force to become resistant to current drug treatment. Pfizer and other drug manufacturers are tasked with modification of their drug formulas to defeat viral and bacterial evolution.

In Fleury’s history of pandemics, listeners/readers will find interesting facts that parallel today’s Covid19’ experience.  A striking parallel is the 1918 Flu pandemic. It killed an estimated 50-100 million people. 

Today the world has lost over 2.5 million people from Covid19, but it pales against the 1918 pandemic’ loss of an estimated 50 to 100 million people.

The 1918 world population is estimated at 1.8 billion.   The world’s population today is at 7.674 billion, over a six-fold increase.  Today’s 2.5 million people lost from Covid19 could become several times greater based on today’s population.

This reminds one of the Texas and Mississippi governors’ choice to return to business as usual with no mask mandates and reopened businesses.

It may be that medical science and vaccination is so much better today than in 1918, but these governors are gambling with American lives.  Covid19 may kill many more.

Fleury reminds reader/listeners of the history of wars and how the microscopic world of poisons, and disease-producing germs were used to defeat combatants.  He notes how small armies were able to defeat large armies.  Fleury tells stories of smaller military forces throwing bags filled with poisonous snakes into enemy camps to create chaos and death, lethal gas use in explosive devices that are thrown into enemy foxholes, and deadly smallpox impregnated blankets given to native Americans by American settlers.  He notes how small expeditionary invasions decimated empires by introducing germs that came from their home countries.  Explorers and soldiers were carriers of germs that had never been seen in the new world.  Millions have died from this newly weaponized unseen world.  Fleury notes that biological research and warfare are ongoing threats to the human race.

In the Sunday NYT’s on 3/7/21, an article criticizes the use of public funds to stockpile an Anthrax vaccine when so many problems have arisen in the fight against Covid19. The complaint largely revolves around one company’s high profitability and government influence in preparing an anthrax antidote stockpile to protect against biological attack by terrorists.

Fleury notes that anthrax bacterium is “…a perennial favorite in every nation’s biological arsenal.” Anthrax causes a rapid and painful death within 12-24 hours and the bacterium can last for 40-80 years in soil.

One has to wonder why can’t government “chew gum and walk” at the same time. Stockpiling an Anthrax antidote and being prepared for a Covid19 type of pandemic could be done at the same time. After all, America is the richest nation in the world.

Many presume Aids has been cured because it is not in the press like it used to be.  Something not widely known is that Aids has no known cure.  It remains a killer.  Only palliative treatment has been found to extend life and Fleury notes the treatment is quite expensive.  Aids is caused by a germ that attacks the immune system.  It is introduced through sexual contact or re-use of hypodermic needles. 

Aids eventually kills nearly all Aids carriers, either from cancer or some other disease that takes advantage of a carrier’s compromised immune system.  Fleury notes an exception is a small minority of carriers with a genetic variation that allows them to live a long life.

Fleury explains there is a race between microbes and humans.  As antibiotic treatment improves, microbes mutate into strains that resist treatment.  What worked yesterday may not work tomorrow.  Fleury implies there is a natural balance among all living things.  Humans may be destined for extinction, but Fleury reminds us of the myth of Pandora.  She left hope in the bottom of the box when all the evils were unloosed on the world.

World leaders struggle with opening their economies at the right time, in the right way, to avoid a return to rising death rates from the Omicron variant of Covid19.

If hope is all that is left, ancient philosophers light different ways to recover. Socrates looks to dialog with others and communication with the gods. Confucius looks to the DAO, i.e., the “way” that gives harmony to human nature. In today’s parlance, talk to the afflicted and pray to your God. For believers in the DAO, seek peace between tribes of the world.

MINDING YOUR BRAIN

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

The Disordered Mind (What Unusual Brains Tell Us About Ourselves)

By: Eric R. Kandel

Narrated by David Stifel

Eric Kandel (Author, Austrian-American MD, Neuroscientist. recipient of the 2000 Nobel Prize in Physiology)

In “The Disordered Mind”, Dr. Kandel offers an explanation of what is known about the physiology of the human brain.  What is thinking?  How does the brain work?  What is consciousness?  What causes brain dysfunction?  What is mental illness? How can mental illness be diagnosed and treated?

Most know there are two distinct halves of the human brain.  What is less well known is that the left and right brain hemispheres conflict with each other.

Kandel explains that right brain activity generates much of human creativity while the left brain is tasked with logic.  It is not that the two halves of the brain never cooperate with each other.  However, regions of the brain frequently interfere with each hemisphere’s understanding of what humans see, feel, hear, and think. With those senses, human thought and action is affected.

MAPPING THE BRAIN

Damage or disease of either side of the brain is a proximate cause of psychiatric disorder but the interconnection of the two sides makes diagnosis and cure a hit and miss proposition.  The physiology of the brain is complex and difficult for today’s practitioners. To diagnose or cure symptoms of brain injury or disease requires precise information about location and physiological characteristics of brain function.  Kandel notes that brain imaging has been a boon to understanding how the brain functions and where thought and action originates and initiates, but interconnectedness thwarts precise understanding.

Kandel informs us of symptoms of various brain injuries and diseases and how science searches, stumbles, and recovers to find ways to ameliorate physical and mental disorders caused by brain dysfunction.  He explains how too much or too little of naturally produced chemicals like dopamine and melatonin affect brain function.  Kandel notes how normal behavior becomes unbalanced with excess or diminishment of brain chemistry.

The origin of artist creativity is explored by Kandel.  Kandel implies the dada movement reflects bizarre subconscious images that titillate the public because they resonate with one’s own subconscious.   

Artists are exhibiting right brain evocations.  This reminds one of Edmund Munch’s Scream and his note hidden in the painting that says, “Could Only Have Been Painted by a Madman”. Kandel dismisses that characterization of artists.  Kandel suggests they are simply magnifying right brain neural activity.

Kandel notes the progress that has been made in abating, if not curing, psychiatric disorder.  It is surprising to find how many treatments have been discovered accidently.  This is not meant to diminish leaps of science in mapping the brain or creating medicinal treatments for psychosis and neuropathy but it discloses much of the luck that leads to palliative, if not curative, care. 

Kandel notes a fundamental cause of certain psychiatric disorders have been found to be misfolded proteins that negatively affect biological activity and, in some cases, increase neuronal toxicity. This misfolding is considered to be a cause of antitrypsin-associated emphysema, cystic fibrosis, and other maladies.

A somewhat surprising disclosure by Kandel is that physical change of the brain is shown from use of psychotherapy as well as physical or chemical intervention.  Kandel suggests psychotherapy is an important part of treatment for patients being treated with drugs or surgical intervention.  Kandel infers physiological change in the brain can be as consequential with psychotherapy as with drug or surgical treatment.  However, he suggests both forms of treatment offer more lasting success.

There is a lot to unpack in Kandel’s book about “The Disordered Mind”.  Many who read/listen to this book will conclude that treatment of drug addiction and other psychological imbalances need more scientific research and better diagnosis and treatment.

GRAVATATIONAL WAVES

Audio-book Review
By Chet Yarbrough

(Blog:awalkingdelight)
Website: chetyarbrough.blog

Black Hole Blues and Other Songs from Outer Space

By: Janna Levin

Narrated by Janna Levin

Janna J. Levin (Author, American theoretical cosmologist and professor of physics.)

Janna Levin writes a brief history of the invention of the Laser, Interferometer, Gravitational-Wave Observatory, LIGO for short.

Janna Levin is a professor of physics and a theoretical cosmologist.  Obviously, a well-educated and intelligent person but not an accomplished writer.  Levin’s history fails to capture a coherent picture of what LIGO is or who the scientists were that pursued understanding of gravitational waves.  The many scientists involved are a confused jumble of characters who are never clearly described except as scientists in pursuit of an elusive discovery. Levin does offer character quirks of many of these scientists but fails to bring them to life. The significance of gravitational waves in Levin’s story seems less stellar because it is given little context in the world of science.

The best one can say about Levin’s story is that it sparks interest in a layman’s understanding of Einstein’s theory of gravitational waves. 

Levin offers some understanding of the subject but misses a succinct description without a listener having to turn to other sources for clarification. Gravitational waves are air particles–that vibrate like a guitar string when it is strummed, or a drum is beat. That is as close as Levin gets to a definition.  Einstein predicted cosmic’ gravitational waves are created when phenomenon like black holes, or “Big Bangs” occur.

One reason Levin’s story holds interest for this critic is that two LIGO’ observatories had to be created to confirm Einstein’s theory.  One was in eastern Washington, the Hanford nuclear reservation, and the other was in Louisiana.  I lived in the Hanford area in the seventies, not as a scientist but as a project manager for a local developer. 

It has always been something of a mystery that eastern Washington continued to develop after WWII when Hanford played a big role in the science of nuclear fission that led to Hiroshima’s and Nagasaki’s bombing.  One thought, Hanford’s nuclear program would wind down with mitigation of nuclear contamination in the area, but the area continues to grow.  LIGO is one of the reasons Richland, Kennewick, and Pasco (known locally as the Tri-Cities where Hanford is located) continues to grow.

One must acknowledge Levin’s story offers some personal insight to the nature of scientific discovery.  She shows how a community of scientists is plagued by the same insecurities and ambitions of any human organization.  There are always organization’ struggles over who is in charge, how internal conflict is resolved, and how money, power, and prestige affect productivity.

Levin implies conflict may be more intense in scientific pursuit because personal motivation is different.  She seems to imply scientists are more motivated by power and prestige than money.  One doubts that is true because humans within any organization have degrees of desire based on all three motives.

The beginning of Levin’s story is with Rainer Weiss, a professor of physics at MIT.  Weiss’s interest in gravitational waves began with his interest in radio waves and refinement of phonographic reproduction. 

As a child, Weiss experimented with speaker systems and refined reproduction through tinkering with how records reproduce music.  Levin suggest Weiss’s personality is deeply affected by his families experience with authority in Germany during the Nazi’s rise to power. 

Weiss pursues his interest in gravitational waves with Soviet scientists, and two Scots named Ronald Drever and James Hough.  Levin imprecisely explains their collaboration and how each conflict with the other over control of the science of gravitational waves.  Drever is a brilliant tinkerer who designs a rudimentary gravitational wave detector.  In 1980, the National Science Foundation funds a large interferometer study at MIT.

Ronald Drever (1931-2017, Scottish pioneer on laser measurement and gravitational wave observation.)

After fits and starts, Rochus Vogt is appointed as director of the development at the LIGO project.  Levin, also a family victim of Nazism, notes that Vogt is an important first director because of his ability to organize scientific research.  However, Vogt is noted as an authoritarian that often conflicts with other scientists (like Drever) who worked on LIGO.

Levin explains Vogt was a manager who resented authority of any kind but had a high degree of organizational skill. Levin suggests Vogt’s family experience with Nazism fed his dislike of supervision or direction from others.

Levin explains Vogt had a great deal to do with successfully raising funds for LIGO’s early development. However, he was eventually fired for his authoritarian way of dismissing other team members ideas and his objection to superiors’ oversight.

Levin notes the massive size and cost of the project which finally locates in two states, Washington, and Louisiana.  Funding is key to its development and is delayed for various reasons.  The politics of science research is touched on by Levin but not clearly defined.  One surmises from Levin’s book that location of expensive projects are as much a political as science-based decision.

There are many pessimists and a few optimists on the value of this research. The time it took to confirm or deny the theory of cosmic gravitational waves is long, expensive, and seemingly serendipitous.  Attempts to prove Einstein’s 1916 theory began in the 1960s, but it takes over 50 years to even begin to prove the existence of gravitational waves.  In the end, Levin recounts the success of these scientists’ efforts on February 22, 2016. 

A gravitational wave is recorded on September 14, 2015, when two black holes collide light years away.  In the following year, the gravitational wave’s finding is fully recognized. The record of the wave confirms Einstein’s theory of gravitational waves.

Without Levin’s final chapter, “Black Hole Blues…” would be a literary failure.  However, with this chapter Levin nearly redeems her story.  Without science, the world would remain in the dark ages; burdened by myth and superstition that distorts the true value of being human.